BDBM10861 4-(2-aminoethyl)benzene-1-sulfonamide::CHEMBL7087::aromatic sulfonamide compound 7::aromatic/heteroaromatic sulfonamide 6

SMILES NCCc1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=FXNSVEQMUYPYJS-UHFFFAOYSA-N

Data  173 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 10861   

TargetCarbonic anhydrase 9(Homo sapiens (Human))
Laxmi Fumigation And Pest Control (P)

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)
Affinity DataKi:  33nMAssay Description:Inhibitory activity against human tumor-associated transmembrane carbonic anhydrase IX.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Laxmi Fumigation And Pest Control (P)

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)
Affinity DataKi:  33nMAssay Description:Inhibitory activity against human carbonic anhydrase IX (hCA IX) by using CO2 hydrase assay methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Laxmi Fumigation And Pest Control (P)

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)
Affinity DataKi:  33nMAssay Description:Inhibitory activity against human cloned carbonic anhydrase isozyme IX, by CO2 hydrase assay method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Laxmi Fumigation And Pest Control (P)

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)
Affinity DataKi:  33nMAssay Description:Inhibition of human carbonic anhydrase 9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Laxmi Fumigation And Pest Control (P)

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)
Affinity DataKi:  33nMAssay Description:Inhibition of human recombinant CA9 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Laxmi Fumigation And Pest Control (P)

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)
Affinity DataKi:  33nMAssay Description:Inhibitory constant against human Carbonic anhydrase IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Laxmi Fumigation And Pest Control (P)

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)
Affinity DataKi:  33nMAssay Description:Inhibition constant against human cloned isozyme (hCA IX) by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Laxmi Fumigation And Pest Control (P)

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)
Affinity DataKi:  33nMAssay Description:Inhibition of human recombinant CA9 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Laxmi Fumigation And Pest Control (P)

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)
Affinity DataKi:  33nMAssay Description:Inhibition of catalytic domain of human recombinant CA IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Laxmi Fumigation And Pest Control (P)

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)
Affinity DataKi:  33nMAssay Description:Inhibitory activity against human carbonic anhydrase IX expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Laxmi Fumigation And Pest Control (P)

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)
Affinity DataKi:  33nMAssay Description:Inhibitory constant against catalytic domain of human carbonic anhydrase IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Laxmi Fumigation And Pest Control (P)

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 expressed in Escherichia coli GOLD BL21 (DE3) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Laxmi Fumigation And Pest Control (P)

Curated by ChEMBL
LigandPNGBDBM10861(4-(2-aminoethyl)benzene-1-sulfonamide | CHEMBL7087...)
Affinity DataKi:  3.30E+4nMAssay Description:Inhibitory activity against human carbonic anhydrase IX at 0.09 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed